p-adic GRN Suite

Interactive analysis of gene regulatory networks via p-adic ultrametric geometry
J.R. Pérez-Buendía · V. Nopal-Coello · Y.-C. Cortés-Poza — CIMAT / UAEH / IIMAS-UNAM, 2025–2026
About

p-adic GRN Suite is a scientific software tool for analyzing Boolean gene regulatory networks (GRNs) using p-adic ultrametric geometry. Given a GRN's discrete transition table, the suite classifies each p-adic ball as Expanding, Attracting, or Indifferent, computes the stability measure μE, finds the optimal gene ordering π* that minimizes instability, and provides interactive visualization of the fractal ball structure, functional transition graph, and algebraic normal form (ANF) polynomial decomposition. The methodology applies to any finite discrete dynamical system with p-adic encoding.

Interactive Applets
Key Features
Included Networks
OrganismN genespStatesμE(π*)
A. thaliana — flowering network 132 8 19226 776
C. elegans — cell cycle network 82 256956
D. melanogaster — gap gene network 62 6464
Custom network (CSV upload) 2–202–4 computed
Citation

If you use this software in your research, please cite both the paper and the software:

Pérez-Buendía, J.R., Nopal-Coello, V., Cortés-Poza, Y.-C. (2025). p-adic analysis of Boolean gene regulatory networks. [Submitted]. Zenodo. https://doi.org/10.5281/zenodo.19805643 Pérez-Buendía, J.R., Nopal-Coello, V., Cortés-Poza, Y.-C. (2025–2026). p-adic GRN Suite (v1.1.0) [Software]. Zenodo. https://doi.org/10.5281/zenodo.19805643 GitHub. https://github.com/yoyontzin/p-adic-grn-suite